Asbestosis symptoms
Asbestosis, which is a type of lung disease, occurs after inhalation of asbestos.[1] It manifests with several symptoms that are common to many other conditions, making it difficult to diagnose. Furthermore, symptoms can take 20 years or more to manifest which also hinders diagnosis.
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[edit] When will the symptoms of asbestosis be experienced?
The symptoms of asbestosis will begin to occur depending on the amount of exposure and length of time exposed to the asbestos fibers. It can take as long as 20 years.
[edit] Common asbestosis symptoms
- Chest pain
- Cough
- Shortness of breath with exertion (slowly gets worse over time)
- Tightness in the chest
- Clubbing of fingers
- Nail abnormalities
[edit] What degree of exposure leads to asbestosis
[edit] Asbestosis treatment
[edit] Studies
1977 Kagan E "Immunological studies of patients with asbestosis." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540761/
"In vitro studies of cellular immunity, as evaluated by phytohaemagglutinin-induced proliferative and cytotoxicity assays, showed significantly lower values amongst the patient group"
1965 Davis JMG "ELECTRON-MICROSCOPE STUDIES OF ASBESTOSIS IN MAN AND ANIMALS" http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1965.tb41093.x/abstract
2001 Liu JY "Increased TGF-beta1 in the lungs of asbestos-exposed rats and mice: reduced expression in TNF-alpha receptor knockout mice" http://www.ncbi.nlm.nih.gov/pubmed/11394717
"Most interesting, TGF-beta1 expression is largely absent in the lungs of TNF-alpha receptor knockout mice that fail to develop asbestos-induced IPE"
2006 Fattman CL "Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase" http://www.ncbi.nlm.nih.gov/pubmed/16458190
[edit] References
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